Search results
Sep 3, 2023 · Capping is a common industrial issue during the manufacturing of pharmaceutical tablets. It is influenced by both process and formulation parameters. In this work, a systematic study of the influence of the geometrical features of biconvex tablets on capping occurrence was performed on a model formu …
Aug 10, 2021 · Capping and lamination are common defects occurring during the manufacturing of pharmaceutical tablets. Several studies showed that tablet anisotropy can play a role in the occurrence of such defects. In this work, we propose a new and easy methodology to characterize the anisotropy of flat-faced cy …
Sep 3, 2023 · Brittleness is an important mechanical property. In the classical sense, a material is considered brittle if, during loading, it behaves elastically until failure. Nevertheless, it is also sometimes understood as the fact to be resistant to breakage. In the case of pharmaceutical tablets, three diff …
Mar 1, 2021 · Léo Desbois, …, Vincent Mazel Influence of in line monitored fluid bed granulation process parameters on the stability of Ethinylestradiol International Journal of Pharmaceutics, Volume 496, Issue 2, 2015, pp. 751-758
Capping is an important industrial problem that can arise during the manufacturing of pharmaceutical tablets. It corresponds, for biconvex tablets, to the detachment of one of the cups of the tablet during the ejection from the press or after relaxation. Solutions to this problem remain mainly empirical. Among them, precompression is widely used.One of the most popular explanation of the role ...
May 5, 2018 · Vincent Mazel 1 , Harona Diarra 2 , Jérôme Malvestio 2 , Pierre Tchoreloff 2 Affiliations 1 Université de Bordeaux, CNRS, I2M Bordeaux, 146 rue Léo Saignat, 33000 Bordeaux, France.
Jul 25, 2023 · Indeed, several authors have shown that the value of the tensile strength obtained using diametral compression was around half of the value obtained using three-point bending (Amin and Fell, 2002, Amorós et al., 2008, Podczeck, 2012, Mazel et al., 2014, Hilden et al., 2016).
