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Developmental engineering. at Penn BE. harnessing biological patterning. Our lab works to bring developmental processes that operate in vertebrate embryos and regenerating organs under an engineering control framework, so that we can build better tissues.
Alex Hughes is an Assistant Professor of Bioengineering at the University of Pennsylvania. Originally from California and New Zealand, he graduated with a B.E./B.Sc. in Chemical & Materials Engineering/Pharmacology at the University of Auckland, NZ in 2008.
Research — Alex Hughes Lab. We study developmental rules and synthetically reconstruct tissue patterning. Many diseases arise from a breakdown in tissue structure, including cancers and congenital birth defects.
Publications — Alex Hughes Lab. Viola*, J.M., Liu*, J., Prahl*, L.S., Huang, A., Chan, T.J., Hayward-Lara, G., Porter, C.M., Hughes, A.J. (2022) Tubule jamming in the developing mouse kidney creates cyclical mechanical stresses in nephron-forming niches.
Alex Hughes. ajhughes@seas.upenn.edu Office: 215-573-5233 Cell: 510-219-5206. 371B Hayden Hall 240 S. 33rd St. Philadelphia, PA 19104. Mailing Address. 210 S. 33rd St. Suite 240, Skirkanich Hall Philadelphia, PA 19104. Lab & student offices. 390 Towne Building 220 S. 33rd Street Philadelphia, PA 19104
The Hughes lab aims to understand disorders of tissue organization. We do this using cutting-edge techniques that synthesize principles of engineering and developmental biology.
The Hughes lab is seeking highly motivated researchers to contribute to the study and synthetic engineering of epithelial development. Ph.D. students . We’re adding 1-2 Ph.D. students to our team during BE and/or CAMB recruitment - please apply and mention your interest in the lab!
Welcome to the Hughes Lab! We work to bring developmental processes that operate in vertebrate embryos and regenerating organs under an engineering control framework, so that we can build better tissues.
