Search results
Nov 28, 2023 · The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches.
PSI-BLAST allows the user to build a PSSM (position-specific scoring matrix) using the results of the first BlastP run. PHI-BLAST performs the search but limits alignments to those that match a pattern in the query.
Application error: a client-side exception has occurred (see the browser console for more information).
BLAST definition: 1. to explode or destroy something or someone with explosives, or to break through or hit something…. Learn more.
What is BLAST? The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches.
BLAST is one of the most widely used bioinformatics programs for sequence searching. [4] It addresses a fundamental problem in bioinformatics research. The heuristic algorithm it uses is much faster than other approaches, such as calculating an optimal alignment.
Awash in a sea of data, how do scientists identify the function of a newly cloned gene? Online resources like the Basic Local Alignment Search Tool (BLAST) provide a helping hand.
Mar 17, 2014 · BLAST for beginners introduces students to blastn, a commonly used tool for comparing nucleotide sequences (DNA and RNA). This popular tutorial shows how to do a blast search with a nucleotide sequence, highlights information in the search results, and shows how to interpret the E value and alignment scores.
Jun 23, 2008 · Copyright and Permissions. This manual documents the BLAST (Basic Local Alignment Search Tool) command line applications developed at the National Center for Biotechnology Information (NCBI).
The program compares nucleotide or protein sequences to sequence in a database and calculates the statistical significance of the matches. This chapter first provides an introduction to BLAST and then describes the practical application of different BLAST programs based on the BLAST Quick Start mini-course (www.ncbi.nlm.nih.gov/Class/minicourses).
Jul 1, 2004 · Basic Local Alignment Search Tool (BLAST) is a sequence similarity search program that can be used via a web interface or as a stand-alone tool ( 1, 2 ). There are several types of BLAST to compare all combinations of nucleotide or protein queries with nucleotide or protein databases.
May 3, 2021 · BLAST stands for Basic Local Alignment Search Tool. It is a local alignment algorithm-based tool used for aligning multiple sequences and finding similarities or dissimilarities among various species. In this article, we will explain different kinds of BLAST tools and how does BLAST algorithm works.
The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between protein or nucleotide sequences. The program compares nucleotide or protein sequences to sequence in a database and calculates the statistical significance of the matches. This...
Quick start results guide. Guide to BLAST home and search pages. Blast report description. Blast topics. Frequently Asked Questions.
blast翻译：爆炸, 炸毁；爆破, 噪声, 产生巨大噪声;发出刺耳声, 批判, 抨击，严厉批评, 爆炸, 爆炸；爆破, 风, 疾风，狂风;一阵强劲的气流, 噪声, （突然发出的）响声, 事件, 喧嚣的聚会；狂欢…。了解更多。
Aug 3, 2023 · BLAST stands for Basic Local Alignment Search Tool. It is a widely used bioinformatics program that was first introduced by Stephen Altschul et al. in 1990 and has since become one of the most popular tools for sequence similarity search.
Jun 23, 2008 · Sequence similarity searching is one of the more important bioinformatics activities and often provides the first evidence for the function of a newly sequenced gene or piece of sequence. Basic Local Alignment Search Tool (BLAST) is probably the most popular similarity search tool.
Mar 21, 2024 · The Basic Local Alignment Search Tool (BLAST) finds regions of similarity between sequences. The program compares nucleotide or protein sequences and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families.
Local alignments algorithms (such as BLAST) are most often used. A global alignment should only be used on sequences that share significant similarity over most of their extents, and then it will sometimes return a better presentation.
Sep 30, 2022 · Introduction. We will take a high-level view of the steps performed by BLAST to generate an alignment, with an emphasis on the "words" used to seed BLAST alignments, and we'll briefly discuss Expect values. For more detail, see this explanation of the Blast process.
BLAST Highlights. NCBI has recently designed the BLAST interface to improve usability. New features include: A list of search results performed within the past 36 hours; Search strategies that can be saved to MyNCBI; Reorganized home-page links to BLAST forms; Redesigned BLAST forms with usability enhancements; A documentation catalog; Common ...
Dec 15, 2009 · Sequence similarity searching is a very important bioinformatics task. While Basic Local Alignment Search Tool (BLAST) outperforms exact methods through its use of heuristics, the speed of the current BLAST software is suboptimal for very long queries or database sequences.
Jun 23, 2008 · Indexing provides an alternative way to search for initial matches in nucleotide-nucleotide searches (blastn and megablast) by pre-indexing the N-mer locations in a special data structure, called a database index. Using an index can improve search times significantly under certain conditions.
