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My current research focuses on the following areas. The functions of reactive oxygen species (ROS) and antioxidants in plants. Currently, the focus is on the metabolism and functions of ascorbate (vitamin C) and on the production and functions of hydrogen peroxide. Plant and algal metabolism and metabolomics.
Nicholas SMIRNOFF, Professor of Plant Biochemistry | Cited by 19,405 | of University of Exeter, Exeter (UoE) | Read 135 publications | Contact Nicholas SMIRNOFF
Leader of the Exeter Mass Spectrometry Facility, conducting small molecule analysis. Current research includes investigating ROS and antioxidants in plants, metabolomics using LC-MS and GC-MS in plants and algae, and studying high-temperature acclimation in algae and cyanobacteria.
The University of British Columbia. Activities between the University of British Columbia and Exeter include a joint research symposium focused on Community, Culture, Creativity, and Wellbeing held at Exeter in May 2018 and a faculty-led, co-funded initiatives in Sport, Exercise and Health Sciences, Climate Change and Digital Humanities.
Nick Smirnoff’s long term research interest is in the metabolism and functions of vitamin C (ascorbic acid) in plants. His laboratory has discovered the biosynthetic pathway of ascorbate and more recently are focusing on control of its synthesis and accumulation in relation to light and its role in photoprotection of photosynthesis.
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Dec 30, 2022 · The principal H 2 O 2 removers are catalase (in peroxisomes), peroxiredoxins, glutathione peroxidase-like enzymes, and ascorbate peroxidases (Smirnoff and Arnaud, 2019) so that inhibition of their activity could decrease the scavenging of H 2 O 2 produced by background metabolism or apoplast.
