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Estradiol has been tied to the development and progression of cancers such as breast cancer, ovarian cancer and endometrial cancer. Estradiol affects target tissues mainly by interacting with two nuclear receptors called estrogen receptor α (ERα) and estrogen receptor β (ERβ).
Feb 20, 2024 · Estradiol is used to treat menopause symptoms such as hot flashes and vaginal changes, and to prevent osteoporosis (bone loss) in menopausal women. Estradiol is also used to treat low estrogen levels in women with ovarian failure. It is also indicated to treat certain types of breast cancer and prostate cancer.
Feb 8, 2022 · Estrogen is one of two sex hormones commonly associated with people assigned female at birth (AFAB), including cisgender women, transgender men and nonbinary people with vaginas. Along with progesterone, estrogen plays a key role in your reproductive health.
Aug 31, 2023 · Estradiol is substantially more potent than its metabolites, estrone, and estriol at the estrogen receptor level. Estradiol is commonly synthesized as a prodrug ester (for example, estradiol acetate, estradiol valerate) to improve its bioavailability.
Estradiol was first discovered and synthesized in 1933 via reduction of estrone. Subsequently, estradiol was isolated for the first time in 1935. It was also originally known as dihydroxyestrin, dihydrofolliculin, or alpha-estradiol.
Find patient medical information for estradiol oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Mar 9, 2023 · Estradiol is a drug prescribed to treat the symptoms of menopause and prevent bone fractures (osteoporosis), painful uterine bleeding, vaginal pain, dryness, and atrophy associated with menopause. Estradiol is also prescribed for the treatment of breast cancer, and some cases of prostate cancer.
Jan 5, 2022 · But the hormone isn’t all bad. In fact, it has some positive side effects, like protecting your heart and brain, improving muscle mass, boosting your mood and improving your sex life. Ob/Gyn ...
May 18, 2023 · It allows for the growth of breast tissue and secondary sexual characteristics, supports healthy cardiovascular function, and has numerous other effects on the neurological and skeletal systems. 1 5. Estradiol also acts on the neurological, skeletal and cardiovascular systems of men. 4.
Aug 31, 2023 · Estradiol (known as E2) is a type of the sex hormone estrogen. Estradiol is the primary estrogen in the female body during childbearing years. While it supports the reproductive system and fertility, estradiol is also helpful in promoting bone and brain health.
