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  1. In toxicology, the median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 is a toxic unit that measures the lethal dose of a given substance. The value of LD 50 for a substance is the dose required to kill half the members of a tested population after a specified test duration.

  2. May 10, 2024 · LD stands for "Lethal Dose". LD 50 is the amount of a material, given all at once, which causes the death of 50% (one half) of a group of test animals. The LD 50 is one way to measure the short-term poisoning potential (acute toxicity) of a material. Toxicologists can use many kinds of animals but most often testing is done with rats ...

  3. en.wikipedia.org › wiki › Lethal_doseLethal dose - Wikipedia

    The median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 (lethal concentration and time) of a toxin, radiation, or pathogen is the dose required to kill half the members of a tested population after a specified test duration.

  4. Feb 11, 2018 · The median lethal dose, or LD50, is a term used in toxicology as a measurement of a lethal dose of a substance (e.g., pathogen, medication, toxic substance, etc.). Specifically, the LD50 represents the dose at which a substance is lethal for 50% of tested subjects.

  5. Jun 30, 2015 · Median lethal dose, LD 50. Predictably, this is the dose required to kill 50% of a test subject population. LD 50 is identical in definition to TD 50, except the toxic effect is death.

  6. The LD 50 is the dose that kills half (50%) of the animals tested (LD = "lethal dose"). It is a standardized measure for expressing and comparing the toxicity of chemicals. LD 50 values are given for common drugs (e.g. ibuprofen and aspirin), common household ingredients including water, table sugar (sucrose), salt (sodium chloride ...

  7. This online calculator is used to determine and graph the LD50 (median lethal dose) value given a set of experimental data. Data can be from Excel or CSV. Calculator gives equation of dose-response curve as well as graph.