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  1. The Santa Fe Trail was a transportation route opened by the Indigenous people of North America as well as European trappers and traders in the second half of the 18th century. It was later used extensively by people from the United States in the 19th century after the Louisiana Purchase.

  2. Jan 17, 2018 · The Santa Fe Trail, a 900-mile route connecting Franklin, Missouri, to Santa Fe, New Mexico, played a crucial role in America's westward expansion in the 1800s.

  3. Jul 18, 2023 · as trail hands hitched their oxen to freight wagons carrying cargo between western Missouri and Santa Fe, New Mexico. Follow the Santa Fe National Historic Trail through five states and you'll find adventure and evidence of past travelers who made this remarkable trip before you!

  4. Santa Fe Trail, in U.S. history, famed wagon trail from Independence, Missouri, to Santa Fe, New Mexico, an important commercial route (1821–80). It was opened by a trader named William Becknell and used by merchant wagon caravans traveling in parallel columns. Learn more about the Santa Fe Trail.

    • The Editors of Encyclopaedia Britannica
  5. May 20, 2024 · Travel the Trail: Map Timeline 1821 - 1880. William Becknell opened up the Santa Fe Trail, between the Missouri River and the Mexican provincial capital of Santa Fe, in the fall of 1821. The route played a major role in bringing people, goods, and ideas to and from Santa Fe for the next 59 years.

  6. Aug 31, 2020 · From 1821 until 1846, the Santa Fe Trail was a two-way international commercial highway used by both Mexican and American traders. Then, in 1846, the Mexican-American War began, and a few months later, America’s Army of the West followed the Santa Fe Trail westward to successfully invade Mexico.

  7. May 20, 2024 · National Historic Trail. Between 1821 and 1880, the Santa Fe Trail was primarily a commercial highway connecting Missouri and Santa Fe, New Mexico. The route was pioneered by Missouri trader William Becknell, who left Franklin, Missouri in September 1821.