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  1. Apr 17, 2024 · Breathing in ozone is like getting a sunburn on your lungs. What Is Ozone? Ozone (O 3) is a gas molecule composed of three oxygen atoms. Ozone is good up high, bad nearby. The ozone layer found high in the upper atmosphere shields us from much of the sun's ultraviolet radiation.

    • Sulfur Dioxide

      What Is Sulfur Dioxide? Sulfur dioxide (SO 2) is a gaseous...

    • Nitrogen Dioxide

      What Is Nitrogen Dioxide? Nitrogen dioxide, or NO 2, is a...

    • Introduction
    • How Are People Exposed to Ozone?
    • How Does Ozone React in The Respiratory Tract?
    • What Are Ozone's Acute Physiological and Symptom Effects?
    • What Effects Does Ozone Have at The Cellular level?
    • How Does Response Vary Among Individuals?
    • What Are The Effects of Ozone on Mortality?
    • What Are The Other Potential Effects of Short-Term Ozone Exposure?
    • At What Exposure Levels Are Effects observed?
    • What Are The Effects of Recurrent Or Long-Term Exposure to Ozone?

    Breathing ground-level ozone can result in a number of health effects that are observed in broad segments of the population. Some of these effects include: 1. Induction of respiratory symptoms 2. Decrements in lung function 3. Inflammation of airways Respiratory symptoms can include: 1. Coughing 2. Throat irritation 3. Pain, burning, or discomfort ...

    Primary exposure occurs when people breathe ambient air containing ozone. The rate of exposure for a given individual is related to the concentration of ozone in the surrounding air and the amount of air the individual is breathing per minute (minute ventilation). The cumulative amount of exposure is a function of both the rate and duration of expo...

    Because ozone has limited solubility in water, the upper respiratory tract is not as effective in scrubbing ozone from inhaled air as it is for more water soluble pollutants such as sulfur dioxide (SO2) or chlorine gas (Cl2). Consequently, the majority of inhaled ozone reaches the lower respiratory tract and dissolves in the thin layer of epithelia...

    The predominant physiological effect of short-term ozone exposure is being unable to inhale to total lung capacity. Controlled human exposure studies have demonstrated that short-term exposure - up to 8 hours - causes lung function decrements such as reductions in forced expiratory volume in one second (FEV1), and the following respiratory symptoms...

    As a result of short-term exposure, ozone and/or its reactive intermediates cause injury to airway epithelial cells followed by a cascade of other effects. These effects can be measured by a technique known as bronchoalveolar lavage (BAL), in which samples of epithelial lining fluid (ELF) are collected during bronchoscopy on volunteers experimental...

    One striking characteristic of the acute responses to short-term ozone exposure is the large amount of variability that exists among individuals. For example, for a 2-hour exposure to 400 ppb ozone (note: 400 ppb is equal to .4 ppm) that includes 1 hour of heavy exercise, the least responsive individual may experience no symptom or lung function ch...

    Studies show: 1. Ozone is associated with increased mortality 2. The absolute effect of ozone on mortality is considerably higher in older adults 3. The ozone-mortality relationship is most prominent during the warm season Recent epidemiologic research has clearly demonstrated that both short-term and longer-term exposures to low concentrations of ...

    Other potential effects of short-term ozone exposure include: 1. hospital admissions and emergency room visits for respiratory causes 2. school absences There is consistent epidemiologic evidence that ambient ozone levels are associated with other markers of respiratory morbidity, particularly during the warm season. In general, studies have report...

    The concentration of ozone at which effects are first observed depends upon the level of sensitivity of the individual as well as the dose delivered to the respiratory tract. The dose, in turn, is a function of the ambient concentration, the minute ventilation, and the duration of exposure. This can be expressed as a rough formula: Dose = Ambient c...

    One of the major unanswered questions about the health effects of ozone is whether repeated episodes of damage, inflammation, and repair induced by years of recurrent short-term ozone exposures result in adverse health effects beyond the acute effects themselves. Daily ozone exposure for a period of 4 days results in an attenuation of some of the a...

  2. International Resources. Overview. CAS No. 10028-15-6. Ozone (O₃) is a colorless to blue gas with a pungent odor. Exposure to ozone may cause headaches, coughing, dry throat, shortness of breath, a heavy feeling in chest, and fluid in the lungs. Higher levels of exposure can lead to more severe symptoms. Chronic exposure may lead to asthma.

  3. Aug 10, 2021 · Ozone is an air pollutant with detrimental effects on lung function. It is generated as a secondary pollutant, involving reactions with nitrogen oxides, 1 and thus varies with levels of these pollutants. This covariance means that real-world effects of ozone on lung function may be particularly difficult to assess in a single epidemiologic study.

    • Stephanie M. Holm, John R. Balmes
    • Chest. 2022 Jan; 161(1): 190-201.
    • 10.1016/j.chest.2021.07.2170
    • 2022/01
  4. Feb 23, 2009 · Inhaling ozone can irritate the airways and cause wheezing, particularly in children and adults who have asthma and chronic obstructive lung disease. However, the biological mechanisms responsible for ozones effects have been poorly understood. A sugar called hyaluronan was recently shown to play a central role in the response to lung injury.

  5. Dec 1, 2020 · Recent findings suggested that long-term exposure to ozone was associated with an increased risk of cardiovascular and respiratory mortality. Longitudinal studies using large cohorts also revealed that long-term exposure to ozone was associated with a greater decline in lung function and the progression of emphysema.

  6. Apr 9, 2024 · Inhaling ozone can cause coughing, shortness of breath, worse asthma or bronchitis symptoms, and irritation and damage to airways.You can reduce your exposure to ozone pollution by checking air quality where you live.