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Sheng Ding is a distinguished investigator at Gladstone Institute of Cardiovascular Disease and UCSF School of Pharmacy. He studies small molecules that control stem cell fate and function in various tissues and diseases.
Articles 1–20. Tsinghua University; Gladstone/UCSF - Cited by 34,146 - stem cell - chemical biology - drug discovery.
Mar 6, 1997 · DING SHENG ENGINEERING PTE LTD was incorporated on 6 March 1997 (Thursday) as a Exempt Private Company Limited by Shares in Singapore. The Company current operating status is live with registered address at MACTECH BUILDING.
丁胜教授是开发和应用全新化学手段研究干细胞和再生医学的引领者，一直致力于发现和鉴定可以调控细胞命运和功能（例如，不同发育阶段及不同组织中干细胞的维持、激活、分化和重编程）的小分子化合物。 截止目前，丁胜教授已经发表了100多篇科研论文，研究综述和书籍章节，并在干细胞领域作出多项重要贡献。 此外，丁胜教授还作为共同创始人，参与创建了多家生物技术公司。 研究方向....
- Zhang M, Lin YH, Sun YJ, Zhu S, Zheng J, Liu K, Cao N, Li K, Huang Y, Ding S. Pharmacological Reprogramming of Fibroblasts into Neural Stem Cells by Signaling-Directed Transcriptional Activation.
- Cao N, Huang Y, Zheng J, Spencer CI, Zhang Y, Fu JD, Nie B, Xie M, Zhang M, Wang H, Ma T, Xu T, Shi G, Srivastava D, Ding S. Conversion of human fibroblasts into functional cardiomyocytes by small molecules.
- Zhang Y, Cao N, Huang Y, Spencer CI, Fu JD, Yu C, Liu K, Nie B, Xu T, Li K, Xu S, Bruneau BG, Srivastava D, Ding S. Expandable Cardiovascular Progenitor Cells Reprogrammed from Fibroblasts.
- Zhu S, Russ HA, Wang X, Zhang M, Ma T, Xu T, Tang S, Hebrok M, Ding S. Human pancreatic beta-like cells converted from fibroblasts. Nat Commun. 2016 Jan 6;7:10080.
Sheng Ding and his team at Tsinghua University School of Pharmaceutical Sciences identify a drug cocktail that induces totipotent stem cells from pluripotent stem cells. Totipotent cells can turn into an entire organism on their own and have the potential to rejuvenate life.
Dr. Sheng Ding is currently William K. Bowes, Jr. Distinguished Investigator and Professor at Gladstone Institute of Cardiovascular Disease, and Department of Pharmaceutical Chemistry, University of California San Francisco.
