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John Bertram is a world leader in quantitative kidney pathology, counting and measuring kidney-filtering units and cells. He studies how environmental and genetic factors affect glomerular and podocyte numbers and their relation to chronic diseases.
The Bertram Lab, led by Professor John Bertram, studies the causes and consequences of low nephron and podocyte endowment and their links with disease. The lab uses high resolution imaging and genetics to investigate kidney development, programming and disease in humans and animals.
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Podocyte number and disease Podocytes are key components of the glomerular filtration barrier. Podocyte loss and injury are key steps that lead to glomerular damage and loss in many forms of kidney disease. Podocytes have little, if any, capacity to be replaced making podocyte protection clinically important. In collaboration with Monash scientists and clinicians and clinicians at the Jikei School of Medicine (Dr Nobou Tsuboi) in Tokyo, we are assessing podocyte number and size in various dis...
Techniques/expertise
Our studies of kidney development and regeneration utilise a wide range of molecular, physiological and morphological techniques. These include cell and tissue culture (including culture of whole embryonic mouse and rat kidneys, culture of specific subcompartments of developing kidneys, culture of specific cell lines), fluorescence-activated cell sorting (FACS), laser capture microdissection, manual microdissection, imaging [including phase, DIC, fluorescence, confocal microscopy, image analy...
We collaborate with many scientists and research organisations around the world. Some of our more significant national and international collaborators are listed below. Click on the mapto see the details for each of these collaborators (dive into specific publications and outputs by clicking on the dots). We collaborate with researchers from: 1. th...
The Bertram Lab offers a variety of Honours, Masters and PhD projects for students interested in joining our group. There are also a number of short-term research opportunities available. You are encouraged to contactProfessor John Betram regarding potential projects that align with the presented research themes.
Learn about the research of Professor John Bertram and his team on kidney development, function and disease. They count and measure kidney parts, such as nephrons and glomeruli, and explore how they are influenced by environmental and genetic factors.
John Bertram is a Professor in the Department of Anatomy and Developmental Biology and the Biomedicine Discovery Institute at Monash University in Melbourne,...
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Oct 11, 2020 · Professor John Bertram, Monash Biomedicine Discovery Institute (BDI) scientist and world-renowned kidney expert, has had a Special Issue of the highly respected US journal The Anatomical Record devoted to his achievements as a researcher and longstanding department head.
John BERTRAM, Professor and Head of Department | Cited by 14,085 | of Monash University (Australia), Melbourne | Read 421 publications | Contact John BERTRAM
Filtering the good from the bad: A focus on kidney development and disease to celebrate John Bertram's long-standing career in anatomy and renal research
