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  1. Jan 11, 2022 · Definition. Wrinkles are lines or creases of the skin that appear as a natural part of aging. The aging process produces loss of skin thickness and elasticity, resulting in progressive skin atrophy, laxity, and wrinkling. These cutaneous alterations are exacerbated by the actinic damage of chronic sun exposure.

  2. Sep 17, 2024 · Wernicke's encephalopathy is an acute neurological emergency caused by thiamine (vitamin B1) deficiency. Under-diagnosed in clinical practice. Most commonly associated with poor dietary intake and/or malabsorption of thiamine, particularly in chronic alcohol-use disorder. Neurological manifestations are varied but typically include altered ...

  3. Sep 12, 2023 · Once a trauma survey has been completed, perform a focused examination of the clavicle and shoulder girdle. Assess any soft tissue swelling and ecchymosis in the area of the clavicle. Determine point tenderness on palpation; gross deformity may be present if the fracture is displaced and/or angulated. Order clavicle x-rays for all patients with ...

  4. Oct 14, 2021 · Noonan syndrome is a relatively common, autosomal-dominant inherited disorder. Characteristic phenotype includes short stature, chest deformity, congenital heart defects, and unusual facial features. Boys frequently present with cryptorchidism and manifest delayed puberty. Caused by activating mutations in multiple genes in the Ras/mitogen ...

  5. Aug 31, 2023 · Definition. Cutaneous larva migrans (CLM) is a self-limiting dermatosis caused by the migration of animal hookworm larvae (most commonly the dog hookworm Ancylostoma caninum and the cat hookworm Ancylostoma braziliense) in the skin. It is characterised by serpiginous or linear raised erythematous tracks that are usually intensely pruritic and ...

  6. Jan 24, 2024 · Summary. Nappy rash is primarily an irritant contact dermatitis. It is most common in the first 2 years of life, but can occur in a person of any age who routinely wears nappies. Diagnosis is made by characteristic skin findings in the area of the body covered by a nappy; erythema of the convex surfaces of the buttocks is the classic finding.

  7. Nov 15, 2023 · Summary. Lichen planus is an idiopathic inflammatory disease affecting the skin, hair, nails, and mucous membranes, usually self-limiting in nature. Characteristic eruption consists of itchy, shiny, flat-topped violaceous papules and plaques favoring the extremities. White net-like patches or ulceration of mucous membranes, nail deformity ...

  8. Browse BMJ Best Practice dermatology specialty and related medical content to help you make evidence-based clinical decisions

  9. Mar 23, 2023 · Definition. Systemic candidiasis (acute disseminated candidiasis) is an infection of blood or other normally sterile site (e.g., pleural and peritoneal fluid) with Candida species, usually in association with fever, hypotension, and/or leukocytosis.Candidemia, or bloodstream infection, is the most common form of systemic candidiasis.

  10. Aug 28, 2024 · Summary. Short stature is defined as a height that is 2 or more standard deviations (SD) below the mean for age and sex within a population (below the 2.5th percentile). Growth deceleration is defined as a growth velocity that is below the 5th percentile for age and sex (e.g., <5 cm/year after the age of 5 years), or a height drop across 2 or ...