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  1. www.science.org › blogs › pipelineIn the Pipeline by Derek Lowe | Science - AAAS

    Oct 2, 2024 · Derek Lowe. 30 Sep 2024. The FDA recently approved a new drug for schizophrenia treatment, but that statement needs a few qualifiers. The pill is actually a mixture of two drugs (we'll get to that in a minute) and the main ingredient is not exactly new, having been discovered over thirty years ago.

  2. www.science.org › content › blog-postWelcome to "In the Pipeline" - Science | AAAS

    Aug 3, 2015 · Derek Lowe’s commentary on drug discovery and the pharma industry. An editorially independent blog, all content is Derek’s own, and he does not in any way speak for his employer.

  3. www.science.org › blogs › pipelineIn the Pipeline by Derek Lowe | Science - AAAS

    Jun 25, 2024 · Derek Lowe’s commentary on drug discovery and the pharma industry. An editorially independent blog, all content is Derek’s own, and he does not in any way speak for his employer. If you have any questions for Derek, please email him at [email protected].

  4. www.science.org › content › blog-postFaked Beta-Amyloid Data. What Does It Mean? | Science - AAAS

    Jul 25, 2022 · In the mid-1980s, the main protein in the plaques was conclusively identified as what became known as beta-amyloid, a fairly short (36 to 42 amino acid) piece that showed a profound tendency to aggregate into insoluble masses.

  5. www.science.org › content › blog-postWhat To Make Next? How Cells Decide. | Science | AAAS

    Aug 26, 2024 · Derek Lowe’s commentary on drug discovery and the pharma industry. An editorially independent blog, all content is Derek’s own, and he does not in any way speak for his employer.

  6. www.science.org › content › blog-postThings I Won't Work With: Azidoazide Azides, More Or Less

    Jan 9, 2013 · Derek Lowe’s commentary on drug discovery and the pharma industry. An editorially independent blog, all content is Derek’s own, and he does not in any way speak for his employer.

  7. www.science.org › content › blog-postAI and Drug Discovery: Attacking the Right Problems

    Mar 19, 2021 · Derek Lowe’s commentary on drug discovery and the pharma industry. An editorially independent blog, all content is Derek’s own, and he does not in any way speak for his employer.

  8. www.science.org › content › blog-postTarget Based Drug Discovery - A Waste of Time? - Science | AAAS

    Sep 21, 2023 · Derek Lowe’s commentary on drug discovery and the pharma industry. An editorially independent blog, all content is Derek’s own, and he does not in any way speak for his employer.

  9. www.science.org › content › blog-postAI-Generated Clinical Candidates, So Far | Science | AAAS

    Nov 8, 2021 · Derek Lowe’s commentary on drug discovery and the pharma industry. An editorially independent blog, all content is Derek’s own, and he does not in any way speak for his employer.

  10. www.science.org › content › blog-postThe 2022 Nobel Prize in Chemistry | Science - AAAS

    Oct 5, 2022 · Derek Lowe’s commentary on drug discovery and the pharma industry. An editorially independent blog, all content is Derek’s own, and he does not in any way speak for his employer.