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Jul 1, 2024 · Clopidogrel is used alone or together with aspirin to lessen the chance of a heart attack or stroke. It is given to patients with acute coronary syndrome (ACS), to patients who have already had a heart attack, severe chest pain, or a stroke, or to patients with other circulation problems (eg, peripheral arterial disease) that could cause a ...
2 days ago · - Clopidogrel 300 mg loading dose should be given in patients undergoing PCI within 24 hours of receiving fibrinolytic therapy. Clopidogrel treatment should be continued at 75 mg once a day with ASA 75 mg – 100 mg daily. Combined therapy should be started as early as possible after symptoms start and continued up to 12 months (see section 5.1).
4 days ago · Multiple DAPT de-escalation treatment strategies, including switching from prasugrel or ticagrelor to clopidogrel, reducing the dose of prasugrel or ticagrelor, and shortening DAPT duration while maintaining monotherapy with ticagrelor, have been consistently shown to reduce bleeding without increasing fatal or nonfatal cardiovascular or cerebral ischemic risks compared with 12-month DAPT.
Jul 17, 2024 · Information About Clopidogrel. Uses of Clopidogrel. Clopidogrel is commonly used in the treatment of heart attack and unstable angina. How Clopidogrel Works. Clopidogrel is a thrombolytic agent which works by inhibiting platelet aggregation.
Jul 15, 2024 · Adding clopidogrel to aspirin is no more effective in preventing recurrent stroke than taking aspirin alone in patients with subcortical stroke, and actually increases the risk for major bleeding and mortality.
Jul 7, 2024 · From the COMMIT (Clopidogrel and Metoprolol in Myocardial Infarction Trial) trial we know that patients with acute MI managed medically either with fibrinolysis, or more conservatively, with just plain old medical therapy and not percutaneous coronary intervention (PCI), had a reduction in ischemic events with clopidogrel vs placebo ...
2 days ago · CABG within five days from clopidogrel is associated with modest increase in operative mortality and re-exploration for bleeding and substantial increase in blood product utilization. Risks decreased with increasing time from discontinuation, plateauing after 3 days from clopidogrel.
