Yahoo Web Search

Search results

1. pubmed.ncbi.nlm.nih.gov › 27111891TAD disruption as oncogenic driver - PubMed

   pubmed.ncbi.nlm.nih.gov › 27111891

   Abstract. Topologically Associating Domains (TADs) are conserved during evolution and play roles in guiding and constraining long-range regulation of gene expression. Disruption of TAD boundaries results in aberrant gene expression by exposing genes to inappropriate regulatory elements.

   • Activation of proto-oncogenes by disruption of chromosome neighborhoods

     We mapped insulated neighborhoods in T cell acute...

2. www.nature.com › articles › s41556/019/0406-2A chromosome folding intermediate at the condensin-to-cohesin ......

   www.nature.com › articles › s41556/019/0406-2

   Nov 4, 2019 · Anne-Laure Valton, Sergey V. Venev, Hakan Ozadam, A. Nicole Fox & Job Dekker. Nature Cell Biology 21 , 1393–1402 ( 2019) Cite this article. 10k Accesses. 116 Citations. 61 Altmetric....

   • Author: Kristin Abramo, Anne-Laure Valton, Sergey V. Venev, Hakan Ozadam, A. Nicole Fox, A. Nicole Fox, Job ...

   • Publish Year: 2019

3. Images

   • 
   • 
   • 
   • 
   • 

   View all

4. www.science.org › doi › 10Activation of proto-oncogenes by disruption of chromosome ... -...

   www.science.org › doi › 10

   Anne-Laure Valton Program in Systems Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA. View all articles by this author

   • Author: Denes Hnisz, Abraham S. Weintraub, Daniel S. Day, Anne-Laure Valton, Rasmus O. Bak, Charles H. Li, J...

   • Publish Year: 2016

5. pubmed.ncbi.nlm.nih.gov › 26940867Activation of proto-oncogenes by disruption of chromosome...

   pubmed.ncbi.nlm.nih.gov › 26940867

   Mar 25, 2016 · We mapped insulated neighborhoods in T cell acute lymphoblastic leukemia (T-ALL) and found that tumor cell genomes contain recurrent microdeletions that eliminate the boundary sites of insulated neighborhoods containing prominent T-ALL proto-oncogenes.

   • Author: Denes Hnisz, Abraham S. Weintraub, Daniel S. Day, Anne-Laure Valton, Rasmus O. Bak, Charles H. Li, J...

   • Publish Year: 2016

6. www.ncbi.nlm.nih.gov › pmc › articlesA cohesin traffic pattern genetically linked to gene regulation

   www.ncbi.nlm.nih.gov › pmc › articles

   Abstract. Cohesin-mediated loop extrusion has been shown to be blocked at specific cis -elements, including CTCF sites, producing patterns of loops and domain boundaries along chromosomes. Here, we explore such cis -elements, and their role in gene regulation.

   • DOI: 10.1038/s41594-022-00890-9

   • Published: 2022/12

7. fr.linkedin.com › in › anne-laure-valton-a2153498Anne-Laure Valton - Chargée de recherche - LinkedIn

   fr.linkedin.com › in › anne-laure-valton-a2153498

   Consultez le profil de Anne-Laure Valton sur LinkedIn, une communauté professionnelle d’un milliard de membres. Chargée de recherche - Research scientist - INRAE · Expérience : INRAE ·...

   • Location: INRAE

8. pubmed.ncbi.nlm.nih.gov › 36482254A cohesin traffic pattern genetically linked to gene regulation

   pubmed.ncbi.nlm.nih.gov › 36482254

   Abstract. Cohesin-mediated loop extrusion has been shown to be blocked at specific cis-elements, including CTCF sites, producing patterns of loops and domain boundaries along chromosomes. Here we explore such cis-elements, and their role in gene regulation.