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  1. In Chinese, the name lingzhi represents a combination of spiritual potency and essence of immortality, and is regarded as the “herb of spiritual potency,” symbolizing success, well-being, divine power, and longevity.

    • Sissi Wachtel-Galor, John Yuen, John A. Buswell, Iris F. F. Benzie
    • 2011
    • 2011
  2. Jul 24, 2021 · Lingzhi Ye. Show all 5 authors. Citations (25) References (152) Abstract. Mitochondria play an essential role in supplying energy for the health and survival of neurons. Mitophagy is a...

  3. Jul 24, 2021 · Mitophagy is a metabolic process that removes dysfunctional or redundant mitochondria. This process preserves mitochondrial health. However, defective mitophagy triggers the accumulation of damaged mitochondria, causing major neurodegenerative disorders.

    • Xufeng Cen, Manke Zhang, Mengxin Zhou, Lingzhi Ye, Hongguang Xia
    • 2021
  4. Maximising the Effects of Lingzhi. For generations, Lingzhi has been used by Traditional Chinese Medicine (TCM) practitioners to nourish the ‘three treasures’ 1 – jing (essence), qi (vital energy), and shen (spirit).

    • Phylogeny
    • Taxonomy
    • Etymology
    • Fruitbody
    • Hyphal Structure
    • Context
    • Tubes
    • Cutis
    • Spores
    • Additional Specimens

    The nuc-ITS dataset contains 53 sequences representing 12 taxa. Amplification of the nuc-ITS region yielded approximately 650 bp fragments. After deleting the ambiguous sites at both ends and 5.8S region in the alignment, 409 characters remained for phylogenetic analysis. For MP analysis, 286 characters are constant, 33 characters are variable, but...

    Ganoderma lingzhi Sheng H. Wu, Y. Cao & Y.C. Dai, sp. nov. (Figs. 2, 3) MycoBank no.: MB 564240 CHINA. Hubei Province, Wuhan, Jiufeng National Forest Park, alt. 90 m, on the ground in forest of Quercus, 29 June 2010, Wu 1006–38(holotype in TNM, isotype in BJFC, IFP).

    lingzhi (Lat.): referring to the Chinese name “Lingzhi”, a highly prized Ganodermafungus in Chinese folklore.

    Basidiocarps annual, stipitate, corky and without odor, but bitter when fresh, becoming hard corky to woody hard when dry. Pilei variable, from semicircle, shell-like, reniform to circular, occasionally lobed, corky, projecting up to 16 cm, 17 cm broad and 2.7 cm thick. Pileal surface weakly laccate when juvenile, strongly laccate with age, cinnamo...

    Hyphal system trimitic; generative hyphae bearing clamp connections, hyaline, thin-walled, infrequent; skeletal hyphae dominant, thick-walled to subsolid, frequently dichotomous branched; binding hyphae thick-walled with a narrow lumen to subsolid; all the hyphae IKI–, CB+; tissues darkening in KOH.

    Generative hyphae not observed; skeletal hyphae dominant, pale brown to brown, thick-walled to subsolid, frequently branched, interwoven, 3–4.5 μm in diam; binding hyphae abundant, brownish, thick-walled with a narrow lumen to subsolid, flexuous, interwoven, 1–2.1 μm in diam.

    Generative hyphae hyaline, thin-walled, moderately branched and clamped, 1.3–2.8 μm in diam; skeletal hyphae dominant, pale brown to distinctly brown, thick-walled with a medium or narrow lumen to subsolid, frequently branched, strongly interwoven, 2–4 μm in diam; binding hyphae brownish, thick-walled to almost solid, frequently branched, flexuous,...

    Composed of a vertical and closely-packed palisade of cells; cells clavate, brown, thick-walled to subsolid, occasionally with blunt outgrowths or protuberances in the apical or lateral parts, moderately to strongly amyloid at maturity, 30–50 × 5–10 μm.

    Basidiospores ellipsoid, truncate at maturity, yellowish brown, IKI–, CB+, double-walled, exospore smooth, endospore with moderate to coarse echinulae, sometimes even to short ridges up to 1.2 μm long, (8–)9–10.7(–12) × (5.2–)5.8–7(–7.5) μm, L = 9.74 μm, W = 6.38 μm, Q = 1.45–1.59 (n = 300/10; the exospore included and the turgid vesicular appendix...

    (paratypes in IFP or mentioned by herbarium code) studied. China. Anhui Province, Hefei, on dead tree of Quercus, 25 September 2008, Dai 10631. Hubei Province, Wuhan, Maanshan National Forest Park, on the ground in forest of Quercus, 30 June 2010, Wu 1006-75 (TNM), Wu 1006-76 (TNM). Hunan Province, Changsha, Yuelushan, on root of Castanopsis, 14. J...

    • Yun Cao, Sheng-Hua Wu, Yu-Cheng Dai, Yu-Cheng Dai
    • 2012
  5. Mar 9, 2007 · Lingzhi ( Ganoderma lucidum) is a woody mushroom highly regarded in traditional medicine and is widely consumed in the belief that it promotes health and longevity, lowers the risk of cancer and heart disease and boosts the immune system.

  6. Nov 14, 2022 · Summary. There are two main pathways of protein degradation in vivo: proteasome and lysosome. As a conserved intracellular process, autophagy delivers cargoes such as proteins or organelles to lysosomes for degradation, which is an important pathway of lysosomal degradation.