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Estradiol has been tied to the development and progression of cancers such as breast cancer, ovarian cancer and endometrial cancer. Estradiol affects target tissues mainly by interacting with two nuclear receptors called estrogen receptor α (ERα) and estrogen receptor β (ERβ).
Feb 20, 2024 · Estradiol is used to treat menopause symptoms such as hot flashes and vaginal changes, and to prevent osteoporosis (bone loss) in menopausal women. Estradiol is also used to treat low estrogen levels in women with ovarian failure. It is also indicated to treat certain types of breast cancer and prostate cancer.
Aug 31, 2023 · Estradiol is substantially more potent than its metabolites, estrone, and estriol at the estrogen receptor level. Estradiol is commonly synthesized as a prodrug ester (for example, estradiol acetate, estradiol valerate) to improve its bioavailability.
Feb 8, 2022 · Estrogen is one of two sex hormones commonly associated with people assigned female at birth (AFAB), including cisgender women, transgender men and nonbinary people with vaginas. Along with progesterone, estrogen plays a key role in your reproductive health.
Find patient medical information for estradiol oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Mar 9, 2023 · Estradiol is a drug prescribed to treat the symptoms of menopause and prevent bone fractures (osteoporosis), painful uterine bleeding, vaginal pain, dryness, and atrophy associated with menopause. Estradiol is also prescribed for the treatment of breast cancer, and some cases of prostate cancer.
Estradiol acts on the on the estrogen receptors to relieve vasomotor systems (such as hot flashes) and urogenital symptoms (such as vaginal dryness and dyspareunia). 18,19,20. Estradiol has also been shown to exert favorable effects on bone density by inhibiting bone resorption.
