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Henri Laborit (21 November 1914 – 18 May 1995) was a French surgeon, neurobiologist, writer and philosopher. In 1952, Laborit was instrumental in the development of the drug chlorpromazine, published his findings, and convinced three psychiatrists to test it on a patient, resulting in great success.
Henri Laborit was one of the founders of modern neuropsychopharmacology, having discovered, or participated in, the discovery of chlorpromazine, gamma-OH, clomethiazole, and minaprine. He also put forward a theory regarding the necessity of counteracting the negative consequences of defense mechanisms during anesthesia or behavioral inhibition.
- Edward Kunz
- 10.31887/DCNS.2014.16.1/ekunz
- 2014
- 2014/03
Jun 3, 2013 · In the early 1950s French physician Henri Laborit experienced a moment of serendipity that would fundamentally alter the landscape of psychiatry and mental illness.
Henri Laborit was a surgeon who found that chlorpromazine, a drug used to reduce surgical shock, also had a calming effect on his patients. He shared his discovery with Pierre Deniker, a psychiatrist who tested the drug on severely ill patients and convinced the U.S. to approve it.
In 1949, Henri-Marie Laborit, a French army surgeon, used promethazine, a phenothiazine derivative, along with barbiturates, to prevent surgical shock and called this “lytic cocktail.” He also noticed that the patients who were extremely anxious were made calm, relaxed and indifferent to the surroundings.
- Chaitra T Ramachandraiah, Narayana Subramaniam, Manuel Tancer
- 2009
Oct 29, 2014 · This essay explores the work of Henri Laborit, the French cyberneticist renowned for his injection of cybernetic theory into urban cultural analysis.
Sep 1, 2013 · Henri Laborit (1914-1995) was a French military MD. He contributed to the discovery of an important molecule that has changed the face of psychiatry, namely chlorpromazine, which became the first...
