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  1. DeSoto County is a county located on the northwestern border of the U.S. state of Mississippi. As of the 2020 census, the population was 185,314, making it the third-most populous county in Mississippi. Its county seat is Hernando. DeSoto County is part of the Memphis metropolitan area. It is the second-most populous county in that ...

  2. Ag-Ed Groundbreaking. Nearly 100 people braved the blistering 100-degree heat on August 25, to commemorate the groundbreaking of the DeSoto County Ag-Ed Center and Arena. “This is a day we’ve been working on for more than 10 years,” said Supervisor Lee Caldwell.

  3. Five cities, new experiences of attractions, food and fun, sports and relaxation you can enjoy in DeSoto County MS. Kids of all ages love DeSoto County!

  4. About DeSoto County. Download the Visitor's Guide. Resources for Meeting Planners. Contact DeSoto County Tourism

  5. Located in the northwestern corner of the state, DeSoto County is bounded by the Mississippi River to the west, Tennessee to the north, and the Coldwater River and Arkabutla Lake to the south. DeSoto was established on 9 February 1836 from land ceded to the United States by the Chickasaw Nation under the 1832 Treaty […]

  6. DeSoto County values our seniors and work hard to make DeSoto County a great place to live, which includes an affordable cost of living, low taxes, low crime rate, quality medical care, parks and recreation, and a variety of cultural activities.

  7. About DeSoto County. Interested in our history? We've got it! DeSoto County was formed in 1836. The county and one of our cities was named after Hernando DeSoto who was the first European explorer to see the Mississippi River. Discover our historic courthouse.