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- www.ncbi.nlm.nih.gov
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Feb 1, 2021 · It was found that it has a wide range of therapeutic properties, including antioxidant, antibacterial, antiviral, anti-fungal, anti-diabetic, anti-inflammatory, anti-hypertensive, antiarrhythmic, wound healing, and liver protection benefits.
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Sep 30, 2016 · In an experimental model of carcinogenesis, tualang and manuka honey administered to rats at a dose of 1 g/kg body weight, a week before the induction of breast carcinogenesis with N-methyl-N-nitrosourea, significantly inhibited tumour development, with manuka honey being more effective than tualang honey .
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Dec 2, 2013 · Manuka honey exerts its apoptotic effect on cancer cells through the induction of the caspase 9 which in turn activates the caspase-3, the executor protein. Apoptosis induced by Manuka also involves induction of DNA fragmentation, activation of PARP, and loss of Bcl-2 expression [ 31 ].
Apr 11, 2024 · Highlights from the study included, “Manuka honey enhances 5-FU-induced apoptosis, regulating intrinsic and extrinsic pathway.”. [1] Manuka honey was also found in this study to have anti-metastasis effects when combined with 5-FU, decreasing the migration of the cancer cells.
May 23, 2023 · Manuka honey may help prevent infections and promote wound healing when used externally. Manuka honey can help fight bacterial infections and has been used in dressings to promote wound healing. Methylglyoxal, a major compound in this honey, is thought to be responsible for these effects.
Dec 3, 2019 · These studies stipulate that in addition to its anti-bacterial effects, MG also contributes to the anti-cancer potential of manuka honey. In a human gastric cancer cell line (SGC-7901), treatment with galangin and quercetin increased the number of apoptotic cells compared with control.
Feb 7, 2013 · In this study, we investigated the antiproliferative activity of manuka honey on three different cancer cell lines, murine melanoma (B16.F1) and colorectal carcinoma (CT26) as well as human breast cancer (MCF-7) cells in vitro.
Apr 13, 2021 · The Immunomodulatory Effects of Honey and Associated Flavonoids in Cancer. by. Razan J. Masad. 1, Shoja M. Haneefa. 1, Yassir A. Mohamed. 1, Ashraf Al-Sbiei. 2, Ghada Bashir. 1, Maria J. Fernandez-Cabezudo. 2 and. Basel K. al-Ramadi. 1,3,*
Apr 25, 2018 · Manuka honey (MH) represents a good source of phenolic compounds such as luteolin, kaempferol, quercetin, gallic acid and syringic acid. The aim of this work was to evaluate the chemopreventive effects of MH on human colon cancer HCT-116 and LoVo cells.
Jun 6, 2024 · Colorectal cancer often leads to metastasis, with cancer stem cells (CSCs) playing a pivotal role in this process. Two closely linked mechanisms, epithelial–mesenchymal transition and angiogenesis, contribute to metastasis and recent research has also highlighted the impact of telomere replication on this harmful t
