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  1. The chart above shows that the bioavailability of newer generation nasal steroids i.e. Nasonex (Mometasone Furoate), Avamys (Fluticasone Furoate), and Flixonase (Fluticasone Propionate) is much lower than Rhinocort (Budesonide) and Nasacort (Triamcinolone Acetonide).

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    • Overview
    • Drug features
    • Cost, availability, and insurance
    • Side effects
    • Drug interactions
    • Use with other medical conditions
    • Talk with your doctor

    Introduction

    Flonase and Nasonex are allergy medications that belong to a class of drugs called corticosteroids. They can reduce inflammation caused by allergies.

    Both Flonase and Nasonex are used to treat allergic rhinitis, which is inflammation of the lining of the nose. Symptoms of this condition can include sneezing and a stuffy, runny, or itchy nose. These symptoms can be seasonal (occurring during certain seasons, such as spring) or perennial (occurring throughout the year).

    Rhinitis symptoms can also occur without allergies in nonallergic rhinitis, also known as vasomotor rhinitis. Both Flonase and Nasonex can treat nasal symptoms of allergic rhinitis, but Flonase can treat nasal symptoms of nonallergic rhinitis as well.

    Flonase can also treat eye symptoms, such as itchy, watery eyes, from both types of rhinitis. Nasonex, on the other hand, can also be used to treat nasal polyps. Nasal polyps are growths that occur on the lining of the nose or sinuses. They’re caused by long-term swelling and irritation from allergies, asthma, or infection.

    The table below compares other key features of Flonase and Nasonex.

    *OTC: over the counter

    **Brand-name Flonase is available OTC. The generic, fluticasone propionate, is available as both an OTC and prescription drug.

    Both Flonase and Nasonex have generic versions. The generic and brand-name versions of these nasal sprays are available in most pharmacies. Generic versions of Flonase and Nasonex contain the same active ingredients as the brand-name versions, but typically cost less. You can compare current prices of these two drugs at GoodRx.com.

    Typically, OTC drugs such as Flonase Allergy Relief aren’t covered by prescription drug insurance plans. However, your plan may cover OTC Flonase if your doctor writes you a prescription for it.

    The side effects of Flonase and Nasonex are very similar. The tables below compare examples of their possible side effects.

    * with symptoms such as rash, itching, and trouble breathing

    Flonase may interact with HIV drugs, such as:

    •ritonavir (Norvir)

    •atazanavir (Reyataz)

    •indinavir (Chemet, Crixivan)

    •nelfinavir (Viracept)

    •saquinavir (Invirase)

    Both Flonase and Nasonex cause similar problems with similar medical conditions. If you have any of the following medical conditions, you should discuss any precautions or warnings with your doctor before using Flonase or Nasonex:

    •nose sores, injury, or surgery

    •eye problems such as cataracts or glaucoma

    •weakened immune system

    •tuberculosis

    •any untreated viral, bacterial, or fungal infection

    Looking at Flonase and Nasonex side by side, it’s easy to see that these drugs are very similar. However, they do have some differences. The key differences may be:

    •What they treat: Both drugs treat nasal symptoms of allergic rhinitis, but Nasonex also treats nasal polyps, and Flonase also treats eye symptoms.

    •If they need a prescription: Flonase is available OTC without a prescription, but Nasonex isn’t.

    To help you decide which drug may be better for you, talk to your doctor. Together, you can decide if Flonase, Nasonex, or another drug is a good choice for treating your allergy problems.

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  2. Dec 20, 2022 · Avamys is a nasal spray that contains the steroid Fluticasone. It helps to reduce the inflammation in the nasal cavity and is commonly used to reduce symptoms of allergic rhinitis such as sneezing, itchiness and runny or blocked nose.

  3. Mar 17, 2021 · Although fluticasone is the backbone of both fluticasone furoate (FF - Avamys) and fluticasone propionate (FP - Flonase), one should be cognisant that their efficacies are not equivalent.

    • James Fowler, Brian W Rotenberg, Leigh J Sowerby
    • 10.1186/s40463-020-00480-z
    • 2021
    • J Otolaryngol Head Neck Surg. 2021; 50: 18.
  4. Compare Fluticasone Nasal vs Nasonex head-to-head with other drugs for uses, ratings, cost, side effects and interactions.

  5. Mar 17, 2021 · Graphical abstract. Background. In the specialty of Otolaryngology – Head and Neck Surgery, intranasal corticosteroids (INCS) s are the mainstay treatment for inflammatory processes within the nasal cavity. Currently, there are nine INCSs available in Canada (Table 1 ). The utility of INCSs can be appreciated by their pharmacodynamics.

  6. Oct 17, 2023 · Official answer. by Drugs.com. The difference is Flonase is available over-the-counter (OTC) and Nasonex is prescription only. There is no difference in their effect or side effects. Flonase and Nasonex are both corticosteroid nasal sprays that are effective at treating hay fever, perennial allergic rhinitis and allergies.