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    • Dr. Shiro Ishii and Unit 731. During World War II, Imperial Japan committed a number of crimes against humanity. But perhaps few were crueler than the experiments that were conducted at Unit 731.
    • “The Little Albert Experiment” After many months observing young children, John Hopkins University psychologist Dr. John B. Watson concluded that infants could be conditioned to be scared of non-threatening objects or stimuli.
    • The “Monster” Study. These days, any tests carried out on children are subject to strict ethical rules and guidelines. This wasn’t the case back in the 1930s, however.
    • The Stanford Prison Experiment. Off all the ill-advised – and indeed, cruel – experiments North American universities have carried out over the decades, none is more infamous than the Stanford Prison Experiment.
  1. Learn about the history and examples of human experimentation that violates medical ethics, such as Nazi Germany's atrocities, Project MKUltra, and the Tuskegee syphilis experiments. Explore the principles and documents that aim to prevent such abuses, such as the Nuremberg Code and the Declaration of Helsinki.

    • The Prison Doctor Who Did Testicular Transplants. From 1913 to 1951, eugenicist Leo Stanley was the chief surgeon at San Quentin State Prison, California’s oldest correctional institution.
    • The Oncologist Who Injected Cancer Cells Into Patients and Prisoners. During the 1950s and 1960s, Sloan-Kettering Institute oncologist Chester Southam conducted research to learn how people’s immune systems would react when exposed to cancer cells.
    • The Aptly Named ‘Monster Study’ Pioneering speech pathologist Wendell Johnson suffered from severe stuttering that began early in his childhood. His own experience motivated his focus on finding the cause, and hopefully a cure, for stuttering.
    • The Dermatologist Who Used Prisoners As Guinea Pigs. One of the biggest breakthroughs in dermatology was the invention of Retin-A, a cream that can treat sun damage, wrinkles, and other skin conditions.
  2. Oct 15, 2016 · Human experiments were more extensive than often assumed with a minimum of 15,754 documented victims. Experiments rapidly increased from 1942, reaching a high point in 1943. The experiments remained at a high level of intensity despite imminent German defeat in 1945.

    • Paul Weindling, Anna von Villiez, Aleksandra Loewenau, Aleksandra Loewenau, Nichola Farron
    • 10.1016/j.endeavour.2015.10.005
    • 2016
    • Endeavour. 2016 Mar; 40(1): 1-6.
  3. Jan 9, 2019 · What makes some human experiments unethical, and what should we do with the ones that have contributed to current medicine?

  4. Feb 8, 2012 · The investigators exposed 1,308 adults to syphilis, gonorrhoea or chancroid, in some cases using prostitutes to infect prisoners and soldiers. After the experiments were uncovered in 2010, Ramos...

  5. Learn about the ethical issues and historical examples of human experimentation, such as the Tuskegee syphilis study and the U.S. military chemical weapons tests. Explore the dangers of unnecessary drugs, the role of informed consent, and the need for compassion in research.