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1 day ago · Background Amyloid beta protein (Aβ) is a treatment target in Alzheimer’s Disease (AD). Lowering production of its parent protein, APP, has benefits in preclinical models. Posiphen, an orally administered small molecule, binds to an iron-responsive element in APP mRNA and decreases translation of APP and Aβ. To augment human data for Posiphen, we evaluated safety, tolerability and ...
5 days ago · The Wechsler Adult Intelligence Scale (WAIS) is an intelligence test first published in 1955 and designed to measure intelligence in adults and older adolescents. The test was designed by psychologist David Wechsler, who believed that intelligence was made up of a number of different mental abilities rather than a single general ...
1 day ago · A total of 1318 community-dwelling individuals aged 60 years and above were selected and assessed for cognitive frailty using a set of neuropsychology batteries and physical function tests. A binary logistic regression (BLR) was used to identify predictors of CF to be used as items in the screening tool.
1 day ago · Mitchell MJ, Billingsley MM, Haley RM, Wechsler ME, Peppas NA, Langer R. Engineering precision nanoparticles for drug delivery. Nat Rev Drug Discov 2021;20:101-24. DOI PubMed PMC
5 days ago · Manchester United have finally agreed a compensation package with Newcastle for the services of Dan Ashworth. The two clubs have been locked in talks for months after Ashworth emerged as a key...
5 days ago · Dan Ashworth has already hinted at what his first two tasks will be as Manchester United sporting director. The 53-year-old, who joined Newcastle United from Brighton in May 2022, is...
5 days ago · Man United have finally agreed a compensation package with Newcastle United to bring new sporting director Dan Ashworth to Old Trafford
