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3 days ago · Medullary thyroid carcinoma (MTC) is a rare cancer derived from neuroendocrine C-cells of the thyroid. In contrast to other neuroendocrine tumors, a histological grading system was lacking until recently. A novel two-tier grading system based on the presence of high proliferation or necrosis is associated with prognosis. Transcriptomic analysis was conducted on 21 MTCs, including 9 high-grade ...
21 hours ago · Background: Metastatic differentiated thyroid cancer (DTC) represents a molecularly heterogeneous group of cancers with varying radioactive iodine (RAI) and [18F]-fluorodeoxyglucose (FDG) uptake patterns potentially correlated with the degree of de-differentiation through the so-called “flip-flop” phenomenon. However, it is unknown if RAI and FDG uptake patterns correlate with molecular ...
1 day ago · Background The outcome of hepatocellular carcinoma (HCC) is limited by its complex molecular characteristics and changeable tumor microenvironment (TME). Here we focused on elucidating the functional consequences of Maternal embryonic leucine zipper kinase (MELK) in the tumorigenesis, progression and metastasis of HCC, and exploring the effect of MELK on immune cell regulation in the TME ...
2 days ago · Oral Squamous Cell Carcinoma (OSCC) accounts for 90% of malignancies of the oral cavity and originates from the malignant transformation of keratinocytes, the cells which constitute the epithelium of the mucosal lining of the mouth (1). With 377,713 new cases recorded in 2020, OSCC represents the 16 ...
2 days ago · Alfonse Builds and Best Refine. This is a ratings and ranking page for the hero Alfonse: Prince of Askr in Fire Emblem Heroes (FEH). Read on to learn Alfonse's stats at Lv. 40, best builds (including the popular Triple Brazen Alfonse build), best weapon refine, and more.
2 days ago · Primary squamous cell carcinoma (SCC) of the liver, a notably uncommon type of cancer, is frequently linked with diverse hepatic conditions including hepatic cysts, hepatolithiasis, and hepatic teratoma. Literature indicates that only approximately 30 cases of primary SCC of the liver have been documented. Herein, we report a 54-year-old previously healthy patient who was presented with ...
5 days ago · Topics discussed include teenage Alphonse taking the Staten Island Ferry into the city to go to St. Marks Place, the influence of Pressa on Canadian rap, and whether Ian could impress Alphonse by dropping a Broken Arrow reference.
