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  1. 4 days ago · Mutation, an alteration in the genetic material (the genome) of a cell of a living organism or of a virus that is more or less permanent and that can be transmitted to the cell’s or the virus’s descendants. The genomes of organisms are all composed of DNA, whereas viral genomes can be of DNA or RNA.

    • Aneuploidy

      In genetic testing: Genetic mutations …life, increasing the...

    • Codon

      Codon, any of 64 different sequences of three adjacent...

    • Antigenic Shift

      antigenic shift, genetic alteration occurring in an...

    • Chromosomal Disorder

      Chromosomal disorder, any syndrome characterized by...

  2. www.genome.gov › genetics-glossary › MutationMutation

    4 days ago · A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during cell division, exposure to ionizing radiation, exposure to chemicals called mutagens, or infection by viruses.

  3. 5 days ago · The mutation is a point mutation, replacing the normal amino acid valine (V) with phenylalanine (F) in the DNA of one gene. This causes the JAK2 protein to be constantly switched "on," leading to uncontrolled blood cell production.

  4. 3 days ago · Moreover, RiceG2G provided new alleles of known genes, including missense mutations in RFT1 and GW6a as well as SVs in OsSOC1 and GNP1. By examining the cases of known genes that were not prioritized by RiceG2G, we found that the main limitation of RiceG2G was the lack of precise scoring of the effects of noncoding variants.

  5. en.wikipedia.org › wiki › GeneGene - Wikipedia

    2 days ago · Many mutations, however, are deleterious or even lethal, and are removed from populations by natural selection. Genetic disorders are the result of deleterious mutations and can be due to spontaneous mutation in the affected individual, or can be inherited.

  6. 4 days ago · A point mutation occurs in a genome when a single base pair is added, deleted or changed. While most point mutations are benign, they can also have various functional consequences, including changes in gene expression or alterations in encoded proteins.

  7. 3 days ago · A nonsense mutation, or its synonym, a stop mutation, is a change in DNA that causes a protein to terminate or end its translation earlier than expected. This is a common form of mutation in humans and in other animals that causes a shortened or nonfunctional protein to be expressed.