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  1. 4 days ago · Disillusionment grew in the 1960s when she discovered that failed investments by her third husband, Martin Melcher, left her deeply in debt.

  2. 4 days ago · One lucky woman, however, who didn't feel enchanted being proposed to at the Eras tour was Louisa Melcher, who refused her boyfriend's proposal, and took to her more than 500,000 TikTok followers...

  3. 3 days ago · Netflix has dropped the trailer for A Good Girl's Guide to Murder, the series adaptation of the hugely successful, New York Times bestselling mystery YA novel by Holly Jackson. Watch the trailer!

  4. 3 days ago · By: Mirko Parlevliet. June 26, 2024. Netflix has shared the official trailer for A Good Girl’s Guide to Murder, which will launch on the streaming service on August 1, 2024 (excluding the UK/Ireland, Germany, Australia, and New Zealand). Five years ago, schoolgirl Andie Bell was murdered by her boyfriend, Sal Singh.

  5. 2 days ago · In addition to Myers, the cast includes Zain Iqbal, Anna Maxwell Martin, Gary Beadle, Mathew Baynton, India Lillie Davies, Rahul Pattni, ... Jonas Melcher for ZDFneo and Dolly Wells, ...

  6. 2 days ago · The series’ executive producers are Lucy Richer and Danielle Scott-Haughton for the BBC, Matthew Read, Matthew Bouch, and Frith Tiplady for Moonage Pictures, Jonas Melcher for ZDFneo, and Dolly Wells, Holly Jackson, and Poppy Cogan. Florence Walker is also credited as a producer on the series.

  7. 2 days ago · (Top) CHARM consists of a DNA binding domain (DBD) fused to the Dnmt3l domain (D3L) and histone H3 tail. CHARM is targeted to the prion protein (Prnp) promoter, D3L recruits the endogenous methyltransferase DNMT3A, and the H3 tail activates DNMT3A to silence Prnp through methylation of the cytosine-guanine dinucleotide (CpG) island (CGI).