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3 days ago · The role of dopaminergic neurons in modulating striatal dynamics on subsecond timescales remains unclear. Long, Lee et al. show that only potentially supra-physiological dopamine levels are ...
5 days ago · Ketamine, a pharmacological agent that acts as an antagonist of the N-methyl-D-aspartate (NMDA) receptor, has garnered considerable interest because of its notable and expeditious antidepressant properties observed in individuals diagnosed with major depressive disorder (MDD) who exhibit resistance to conventional therapeutic interventions. A comprehensive and rigorous systematic review was ...
1 day ago · Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic chemical of the catecholamine and phenethylamine families. Dopamine constitutes about 80% of the catecholamine content in the brain.
3 days ago · To better understand how neuromodulators affect synaptic processing in ipRGC, we examine actions of opioid and dopamine agonists have on inhibitory synaptic currents in ipRGCs. Although µ-opioid receptor (MOR) activation had no effect on γ-aminobutyric acid (GABA) currents, dopamine (via the D1R) amplified GABAergic currents in a subset of ...
3 days ago · Milica Bogdanovna Jovovich (/ ˈ j oʊ v ə v ɪ tʃ / YOH-və-vitch; born December 17, 1975), known professionally as Milla Jovovich (MEE-lə), is an American actress and former fashion model. Her starring roles in numerous science-fiction and action films led the music channel VH1 to deem her the "reigning queen of kick-butt" in 2006. [3]
5 days ago · To investigate alterations of DAergic transmission in different downstream brain regions, Wu et al. used dopamine sensors to monitor dopamine release in the nucleus accumbens (NAc), the medial prefrontal cortex (mPFC), the hypothalamus (HA), and the dorsal striatum (dStr). 1 During SD, a significant increase in dopamine content was observed within the NAc, the mPFC, and the HA, while no change ...
4 days ago · “Dopamine is a neurotransmitter that helps control the brain’s reward and pleasure centers. Dopamine also helps regulate movement and emotional response, and it enables us not only to see rewards, but to take action to move toward them.”
