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  1. 1 day ago · Martin Mull, who played Colonel Mustard in Clue, Roseanne’s boss Leon Carp in the ABC comedy Roseanne and starred on Norman Lear's Fernwood 2 Nite, died Thursday at his home. He was 80. The news ...

  2. 2 days ago · The Cosby Show is an American television sitcom created by (along with Ed. Weinberger and Michael J. Leeson) and starring Bill Cosby that originally aired on NBC from September 20, 1984, to April 30, 1992, with a total of 201 half-hour episodes spanning eight seasons, including an outtakes special.

    • Sitcom
  3. 3 days ago · Last year, a gene editing therapy to target the blood disorders sickle cell disease and beta thalassaemia became the world’s first Crispr treatment to win regulatory approval. The promising ...

  4. 2 days ago · CRISPRoff has the benefit of a wide and effective targeting window at gene promoters as a result of CpG methylation spreading, and its effect is generally stable through cell division and differentiation. This stands in contrast to CRISPRi (dCas9-KRAB), which enables robust but transient gene repression .

  5. 2 days ago · Weissman and his team also engineered CHARM to switch itself off after it had finished its gene-silencing work, ... Raymond, G. J. et al. JCI Insight 5, e131175 (2019).

  6. 2 days ago · With profound sadness we announce the loss of Charlotte Marie Kelley, our loving and devoted mother, wife and friend. She died unexpectedly on June 20, 2024, while traveling with her friend Rose to the Gathering of Eagles Indigenous Conference in Oregon, Wisconsin. Mom was born December 7, 1938 (85) to Dora and Raymond Helgeson in Lodge Pole, MT.

  7. 1 day ago · Raymond L. Shuman June 13, 1958 February 3, 2018 59 years, 7 months, 20 days United States: Longest serving prisoner in Nevada. Jailed for the robbery and murder of two men while he and his partner (who was the one that pulled the trigger) were AWOL from the US Navy. Set another prisoner on fire in 1973 due to a dispute about leaving a window open.