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  1. pubmed.ncbi.nlm.nih.gov › 12433723Endogenous gonadal hormone exposure and bone sarcoma risk

    To determine whether there was an association between endogenous sex hormones and risk of bone sarcoma, relative risk (RR) of incidence rates and hazard ratios for bone sarcoma were calculated for dogs subdivided on the basis of lifetime gonadal hormone exposure.

    • Dawn M. Cooley, Benjamin C. Beranek, Deborah L. Schlittler, Nita W. Glickman, Lawrence T. Glickman, ...
    • 2002

  2. aacrjournals.org › cebp › articleEndogenous Gonadal Hormone Exposure and Bone Sarcoma Risk

    Nov 1, 2002 · Although experimental and clinical evidence suggest that endogenous sex hormones influence bone sarcoma genesis, the hypothesis has not been adequately tested in an appropriate animal model.

  3. www.wellbeingintlstudiesrepository.org › cgi › viewcontentEndogenous Gonadal Hormone Exposure and Bone Sarcoma Risk

    Table 4 shows the incidence rate of bone sarcoma (per 10,000 dog-months) in each of the gonadal hormone exposure subgroups. There was a significant negative association between gonadal hormone exposure and risk of bone sarcoma (P for trend 0.008 for males; 0.006 for females).

    • Dawn M. Cooley, Benjamin C. Beranek, Deborah L. Schlittler, Nita W. Glickman, Lawrence T. Glickman, ...
    • 2002

  4. link.springer.com › chapter › 10Epidemiology of Bone and Soft Tissue Sarcomas | SpringerLink

    Oct 2, 2020 · However, these factors are not consistent across all bone and soft tissue sarcomas. In this chapter, we review the epidemiology of bone and soft tissue sarcomas, including a discussion of the roles of environmental risk factors, established predisposing syndromes, and other suspected risk factors. Download chapter PDF.

    • Logan Spector, Julie A. Ross, Rajaram Nagarajan
    • 2006

  5. www.ncbi.nlm.nih.gov › pmc › articlesRisk factors for appendicular osteosarcoma occurrence in large...

    Results. A total of 227 client-owned dogs met inclusion criteria for the OSA group, with an age range of 6 mo to 15 y, and a mean age at diagnosis of 7.9 y (SD = 2.9 y). The average weight of dogs recruited in this population was 41.9 kg (SD = 12.5 kg), with a range of 18.3 to 88.5 kg.

  6. www.ncbi.nlm.nih.gov › pmc › articlesNeutering Dogs: Effects on Joint Disorders and Cancers in Golden...

    Feb 13, 2013 · Cooley DM, Beranek BC, Schlittler DL, Glickman MW, Glickman LT, et al. (2002) Endogenous gonadal hormone exposure and bone sarcoma risk. Cancer Epidemiol Biomarkers Prevent 11 : 1434–1440. [ PubMed ] [ Google Scholar ]

  7. europepmc.org › article › MEDCanine bone sarcoma: estimation of relative risk as a function of...

    Cooley DM, Beranek BC, Schlittler DL, Glickman NW, Glickman LT, Waters DJ. Cancer Epidemiol Biomarkers Prev, 11(11):1434-1440, 01 Nov 2002 Cited by: 42 articles | PMID: 12433723