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  1. In toxicology, the median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 is a toxic unit that measures the lethal dose of a given substance. The value of LD 50 for a substance is the dose required to kill half the members of a tested population after a specified test duration.

  2. May 10, 2024 · LD 50 and LC 50 are measures of acute toxicity that indicate the amount or concentration of a chemical that kills or harms 50% of test animals. Learn how these tests are done, what they mean for human health and safety, and how to compare different chemicals.

  3. en.wikipedia.org › wiki › Lethal_doseLethal dose - Wikipedia

    The median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 (lethal concentration and time) of a toxin, radiation, or pathogen is the dose required to kill half the members of a tested population after a specified test duration.

  4. Feb 11, 2018 · Learn what the LD50 is and how it is used to measure the toxicity of a substance. Find out the advantages and drawbacks of this method and see examples of its applications.

  5. Jun 30, 2015 · Median lethal dose, LD 50. Predictably, this is the dose required to kill 50% of a test subject population. LD 50 is identical in definition to TD 50, except the toxic effect is death.

  6. The LD 50 is the dose that kills half (50%) of the animals tested (LD = "lethal dose"). It is a standardized measure for expressing and comparing the toxicity of chemicals. LD 50 values are given for common drugs (e.g. ibuprofen and aspirin), common household ingredients including water, table sugar (sucrose), salt (sodium chloride ...

  7. This online calculator is used to determine and graph the LD50 (median lethal dose) value given a set of experimental data. Data can be from Excel or CSV. Calculator gives equation of dose-response curve as well as graph.