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Examples of miRNA stem-loops, with the mature miRNAs shown in red. MicroRNA ( miRNA) are small, single-stranded, non-coding RNA molecules containing 21 to 23 nucleotides. [1] Found in plants, animals and some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression.
Jun 28, 2023 · In this Review, the authors describe how the application of new technologies to the microRNA (miRNA) field has yielded key insights into miRNA biology.
Aug 3, 2018 · miRNAs are small non-coding RNAs, with an average 22 nucleotides in length. Most miRNAs are transcribed from DNA sequences into primary miRNAs (pri-miRNAs) and processed into precursor miRNAs (pre-miRNAs) and mature miRNAs. In most cases, miRNAs interact with the 3′ UTR of target mRNAs to suppress expression ( 14 ).
- Jacob O'Brien, Heyam Hayder, Yara Zayed, Chun Peng
- 10.3389/fendo.2018.00402
- 2018
- Front Endocrinol (Lausanne). 2018; 9: 402.
MicroRNAs (miRNAs) are a class of small noncoding RNAs, which function in posttranscriptional regulation of gene expression. They are powerful regulators of various cellular activities including cell growth, differentiation, development, and apoptosis.
- Kioomars Saliminejad, Hamid Reza Khorram Khorshid, Shahrzad Soleymani Fard, Seyed Hamidollah Ghaffar...
- 2019
Nov 13, 2007 · MicroRNAs (miRNAs), widely distributed, small regulatory RNA genes, target both messenger RNA (mRNA) degradation and suppression of protein translation based on sequence complementarity between the miRNA and its targeted mRNA. Different names have been used to describe various types of miRNA.
- Shao-Yao Ying, Donald C. Chang, Shi-Lung Lin
- 10.1007/s12033-007-9013-8
- 2008
- Mol Biotechnol. 2008; 38(3): 257-268.
Mar 13, 2012 · MicroRNAs (miRNAs) function as 21–24-nucleotide-long guides that regulate the expression of mRNAs containing complementary sequences. Although plant miRNAs typically base-pair perfectly to ...
Jul 16, 2014 · MicroRNAs (miRNAs) are small non-coding RNAs that function as guide molecules in RNA silencing. Biogenesis of miRNA is under tight temporal and spatial control. Dysregulation of miRNA is ...
