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  1. Welcome to the Chen Lab website! Announcements. April 24, 2024. Congrats to Ximin, Laurence, and Amy for the publication in Nature Metabolism! April 12, 2024. Congrats to Meng-Yin, Chris, Ryan, and team for the publication in Journal of Experimental Medicine! April 1, 2024. Congrats to Sohan for winning the Barry M. Goldwater Scholarship!

  2. Principal Investigator. Yvonne Chen. B.S., Chemical Engineering, Stanford University. Ph.D., Chemical Engineering, California Institute of Technology. Yvonne earned her B.S. in Chemical Engineering from Stanford University and her Ph.D. in Chemical Engineering from the Caltech.

  3. Translation: Humans Cells. Synthetic Biology in the Engineering of CAR-T and CAR-NK Cell Therapies: Facts and Hopes. Clin Cancer Res. 2023 04 14; 29 (8):1390-1402.

  4. Dr. Yvonne Chen's research focuses on applying molecular and synthetic biology techniques to rewire and construct novel biological circuits for applications in health and medicine, particularly in cell-based immunotherapy.

  5. Yvonne Chen, Ph.D., applies biomolecular engineering and synthetic biology principles to advance the development of next-generation adoptive CAR-T cell therapies for cancer. She seeks to enhance the safety, efficacy and applicability of these immunotherapy approaches across a wide range of cancer types. Adoptive T-cell immunotherapy is the ...

  6. Research. Building Synthetic Biological Circuits for Medical Applications. Engineered primary human CD8+ T cell (red) targeting lymphoma cells (green)

  7. Synthetic biology advances and applications in the biotechnology industry: a perspective. L Katz, YY Chen, R Gonzalez, TC Peterson, H Zhao, RH Baltz. Journal of Industrial Microbiology and...