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Sir John Bertrand Gurdon FRS (born 2 October 1933) is a British developmental biologist, best known for his pioneering research in nuclear transplantation and cloning. [1] [5] [6] [7] Awarded the Lasker Award in 2009, in 2012, he and Shinya Yamanaka were jointly awarded the Nobel Prize for Physiology or Medicine for the discovery ...
May 6, 2024 · John Gurdon, British developmental biologist who was the first to demonstrate that egg cells are able to reprogram differentiated (mature) cell nuclei, reverting them to a pluripotent state, in which they regain the capacity to become any type of cell. He won a share of the 2012 Nobel Prize for Physiology or Medicine.
- Kara Rogers
Jan 1, 2017 · John Gurdon is a renowned biologist who cloned the first genetically identical adult animals from somatic cells. He leads a group at the Gurdon Institute in Cambridge, UK, that studies nuclear reprogramming by oocytes and eggs.
Sir John B. Gurdon The Nobel Prize in Physiology or Medicine 2012 . Born: 2 October 1933, Dippenhall, United Kingdom . Affiliation at the time of the award: Gurdon Institute, Cambridge, United Kingdom . Prize motivation: “for the discovery that mature cells can be reprogrammed to become pluripotent” Prize share: 1/2
The Nobel Prize in Physiology or Medicine 2012 was awarded jointly to Sir John B. Gurdon and Shinya Yamanaka "for the discovery that mature cells can be reprogrammed to become pluripotent"
Oct 8, 2012 · John B. Gurdon discovered in 1962 that the specialisation of cells is reversible. In a classic experiment, he replaced the immature cell nucleus in an egg cell of a frog with the nucleus from a mature intestinal cell. This modified egg cell developed into a normal tadpole.
Oct 14, 2019 · John Gurdon and his colleagues challenged the dogma that differentiation is irreversible by showing that nuclei from differentiated cells of Xenopus laevis could support normal development. This landmark paper paved the way for modern methods of reprogramming cell identity and regenerative therapies.
