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  1. Apr 5, 2024 · Parkinson's disease is a progressive disorder that affects the nervous system and the parts of the body controlled by the nerves. Symptoms start slowly. The first symptom may be a barely noticeable tremor in just one hand. Tremors are common, but the disorder also may cause stiffness or slowing of movement.

  2. Parkinson's disease (PD), or simply Parkinson's, is a long-term neurodegenerative disease of mainly the central nervous system that affects both the motor and non-motor systems of the body. The symptoms usually emerge slowly, and as the disease progresses, non-motor symptoms become more common.

  3. Parkinson's disease occurs when the nerve cells in your brain don't make enough of a body chemical called dopamine, which affects your movement and mood. Common symptoms may include tremors, muscle stiffness, slowing of movement and posture changes, but confirming if you have Parkinson's can take time.

  4. Sometimes stiffness goes away as you move. If it does not, it can be a sign of Parkinson's disease. An early sign might be stiffness or pain in your shoulder or hips. People sometimes say their feet seem “stuck to the floor.”.

  5. www.nhs.uk › conditions › parkinsons-diseaseParkinson's disease - NHS

    The main symptoms of Parkinson's disease are: involuntary shaking of particular parts of the body (tremor) slow movement. stiff and inflexible muscles. A person with Parkinson's disease can also experience a wide range of other physical and psychological symptoms. These include: depression and anxiety. balance problems (this may increase the ...

  6. Theory of PD Progression: Braak’s Hypothesis. Researchers believe a combination of genetic and environmental factors cause Parkinson’s. In 2003, Heiko Braak, MD, hypothesized that an unknown pathogen (a bacteria, virus or other microorganism that causes disease) in the gut could be the cause of PD.

  7. Dec 21, 2018 · Parkinson’s disease (PD) is a common neurodegenerative disorder. While a number of non-motor manifestations arise, the typical clinical features involve a movement disorder consisting of bradykinesia, resting tremor, and rigidity, with postural instability occurring at a later stage. The cause of PD is not known, but a number of genetic risk factors have now been characterized, as well as ...

  8. May 18, 2023 · Parkinson's disease is a progressive neurological degeneration of certain cells (called dopaminergic cells) within a specific part of the brain (substantia nigra). The deficiency of dopamine leads to a movement disorder with Parkinson's disease symptoms.

  9. The main symptoms of Parkinson's disease affect physical movement: tremor – shaking, which usually begins in the hand or arm and is more likely to occur when the limb is relaxed and resting. slowness of movement (bradykinesia) – physical movements are much slower than normal, which can make everyday tasks difficult and result in a ...

  10. Parkinson's disease is the most common type of parkinsonism, but there are also some rarer types where a specific cause can be identified. These include parkinsonism caused by: medication (drug-induced parkinsonism) – where symptoms develop after taking certain medications, ...

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