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Yiyun Cheng, A Fluorous Peptide Amphiphile with Potent Antimicrobial Activity for the Treatment of MRSA‐induced Sepsis and Chronic Wound Infection, Angewandte Chemie International Edition, 63, 20, (2024). https://doi.org/10.1002/anie.202403140
- Guangyu Rong, Changping Wang, Lijie Chen, Yang Yan, Yiyun Cheng, Yiyun Cheng
- 2020
Apr 10, 2018 · Yang Yan, Jingjing Hu & Yiyun Cheng. Nature Communications 9, Article number: 1377 ( 2018 ) Cite this article. 15k Accesses. 251 Citations. 5 Altmetric. Metrics. Direct delivery of...
- Zhenjing Zhang, Wanwan Shen, Jing Ling, Yang Yan, Jingjing Hu, Yiyun Cheng
- 2018
Aug 28, 2020 · Guangyu Rong, Changping Wang, Lijie Chen, Yang Yan, Yiyun Cheng. PMID 32851155. ABSTRACT. Cytosolic delivery of peptides remains a challenging task owing to their susceptibility to enzymatic degradation and the existence of multiple intracellular barriers.
Apr 10, 2018 · Here, we report an efficient protein delivery system via the co-assembly of fluoroamphiphiles and proteins into nanoparticles. Fluorous substituents on the amphiphiles play essential roles in the formation of uniform nanoparticles, avoiding protein denaturation, efficient endocytosis, and maintaining low cytotoxicity.
- Zhenjing Zhang, Wanwan Shen, Jing Ling, Yang Yan, Jingjing Hu, Yiyun Cheng
- 2018
Nov 12, 2021 · Based on the high frequency of concurrent adenomatous polyposis coli ( APC) and KRAS mutations and their strong cooperative interaction in human colorectal cancer (CRC) promotion, we herein develop a CRISPR-Cas9-based genome-editing nanomedicine to target both APC and KRAS mutations for the treatment of CRC.
- Tao Wan, Qi Pan, Chongyi Liu, Jiajing Guo, Bowen Li, Xiaojie Yan, Yiyun Cheng, Yuan Ping
- 2021
Jun 10, 2021 · The treatment of malignant bone tumors by chemotherapeutics often receives poor therapeutic response due to the specific physiological bone environment, and thus calls for the development of new therapeutic options. Here, we reported a bone-targeted protein nanomedicine for this purpose.
Feb 17, 2022 · Corpus ID: 246944329. Fluorination Promotes the Cytosolic Delivery of Genes, Proteins, and Peptides. Jia Lv, Hui Wang, +1 author. Yiyun Cheng. Published in Accounts of Chemical Research 17 February 2022. Chemistry, Medicine. TLDR.
