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  1. Nov 13, 2020 · To our knowledge, the ARREST trial is the first randomised interventional trial to assess the effect of early ECMO-facilitated resuscitation compared with standard ACLS treatment for survival of patients with out-of-hospital refractory cardiac arrest.

  2. Aug 27, 2023 · ARREST is the first and only randomised trial of delivery to a cardiac arrest centre following resuscitated OHCA in the community. The success of this trial is attributable to the research infrastructure at the London Ambulance Service and the pan-London cardiac network, which facilitated the success of a trial of this scale and ...

  3. Dec 5, 2020 · The ARREST trial is registered with ClinicalTrials.gov, NCT03880565. Findings: Between Aug 8, 2019, and June 14, 2020, 36 patients were assessed for inclusion. After exclusion of six patients, 30 were randomly assigned to standard ACLS treatment (n=15) or to early ECMO-facilitated resuscitation (n=15).

    • Demetris Yannopoulos, Jason Bartos, Ganesh Raveendran, Emily Walser, John Connett, Thomas A Murray, ...
    • 2020
  4. Nov 13, 2020 · We read with interest about the outcomes of advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation in the ARREST trial. 1

    • Demetris Yannopoulos, Jason Bartos, Ganesh Raveendran, Emily Walser, John Connett, Thomas A Murray, ...
    • 2020
  5. Nov 13, 2020 · The goal of the trial was to evaluate extracorporeal membrane oxygenation (ECMO) initiated in the catheterization laboratory compared with standard advanced cardiac life support (ACLS) among patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation.

  6. Jan 25, 2023 · A previous randomized, controlled trial that compared extracorporeal CPR with conventional CPR in out-of-hospital cardiac arrest owing to ventricular arrhythmias was the ARREST (Advanced ...

  7. Jun 15, 2023 · We conducted the Targeted Therapeutic Mild Hypercapnia after Resuscitated Cardiac Arrest (TAME) trial to test the hypothesis that targeted mild hypercapnia would improve neurologic outcomes at...