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Julia Oh, Ph.D. Associate Professor. Our central goal is to develop microbiome therapeutics to treat human disease. We use diverse tools like genomics and synthetic biology to investigate our microbiome’s role in our health and engineer therapeutics. Visit The Oh Lab. Our central goal is to develop microbiome therapeutics to treat human disease.
- Infectious Disease
Infectious disease is the invasion of body tissues by agents...
- Microbiome
Hidden in the skinJulia Oh probes the depths of human skin...
- Aging
Julia Oh and her team collaborated with the UConn Center on...
- Bioinformatics
Bioinformatics researchers integrate and manage the vast...
- The Jax Cancer Center
The Jackson Laboratory Cancer Center (JAXCC) is a National...
- Genetics and Genomics
Researching entire genomes and systems through genomic...
- Infectious Disease
Members. Julia Oh received her B.A. from Harvard University, her Ph.D. in genetics from Stanford University, and postdoctoral training at the National Institutes of Health.
- Our Research
- Refining The Microbial Blueprint
- The Diseased and Healthy Microbiome
- Engineering The Microbiome: Therapeutics
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The long-term goal of our research program is to create new microbiome-based therapeutics for skin disease, with implications for a wide range of inflammatory diseases. Our lab is dually computational and experimental - we develop advanced algorithms and analyses using shotgun metagenomic sequencing data for the purpose of reconstructing the struct...
Algorithms for improving reference-based and de novometagenomic characterizationsExperimental technologies (single cell, in situ sequencing, high throughput phenotyping) for reconstructing microbiota and host-microbiome interactionsThe genetic architecture and strain diversity of skin commensal Staphylococcus epidermidisand its role in skin health and infectious diseaseDefining the host-microbiome immune interactome – large-scale reconstruction of the complex network linking microbial products to aberrant immune activationLocal and systemic interactions of the gut and skin microbiome in skin cancer progression and immunotherapy responseEngineering Staphylococcus epidermidisas a drug delivery chassisDefining the rules for engineering the skin microbiomeModeling engraftment of foreign microbiota and immune interactions in miceThe Oh Lab at JAX focuses on creating new microbiome-based therapeutics for skin disease and other inflammatory diseases. The lab uses computational and experimental approaches to study the structure, dynamics, and function of the skin, gut, and airway microbiota.
Temporal shifts in the skin microbiome associated with atopic dermatitis disease flares and treatment. HH Kong, J Oh, C Deming, S Conlan, EA Grice, M Beatson, E Nomicos, ... Genome Research. ,...
Mar 12, 2024 · The Jackson Laboratory's Julia Oh, Ph.D., profiles the bacteria populating the skin, including understudied Staphylococcus subtypes. Supported by a recent NIH grant, she will investigate how these microbes interact with skin cells and affect the skin's immune and barrier functions.
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Julia Oh, Ph.D., a Jackson Laboratory (JAX) assistant professor who explores the communities of microorganisms that live on the human skin, has received a special New Innovator Award of $2,835,000 from the National Institutes of Health (NIH) to explore how to develop engineered probiotic treatments for a variety of skin and infectious diseases.