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  1. ProtParam [ Documentation / Reference ] is a tool which allows the computation of various physical and chemical parameters for a given protein stored in UniProtKB or for a user entered protein sequence.

  2. Translate tool. Translate is a tool which allows the translation of a nucleotide (DNA/RNA) sequence to a protein sequence.

  3. Compute pI/Mw for UniProtKB entries or one user-entered sequence. Please enter one or several UniProtKB AC/ID (e.g. P04406 or ALBU_HUMAN ), each on a separate line. Alternatively, enter one protein sequence in single letter code. The theoretical pI and Mw will then be computed.

  4. ProtScale allows you to compute and represent the profile produced by any amino acid scale on a selected protein. An amino acid scale is defined by a numerical value assigned to each type of amino acid.

  5. PeptideMass [ Documentation / References ] cleaves a protein sequence from the UniProt Knowledgebase (Swiss-Prot and TrEMBL) or a user-entered protein sequence with a chosen enzyme, and computes the masses of the generated peptides. The tool also returns theoretical isoelectric point and mass values for the protein of interest.

  6. PeptideCutter [ Documentation / References] predicts potential cleavage sites cleaved by proteases or chemicals in a given protein sequence. PeptideCutter returns the query sequence with the possible cleavage sites mapped on it and /or a table of cleavage site positions.

  7. Operated by the SIB Swiss Institute of Bioinformatics, Expasy, the Swiss Bioinformatics Resource Portal, provides access to scientific databases and software tools in different areas of life sciences.

  8. Expasy is the bioinformatics resource portal of the SIB Swiss Institute of Bioinformatics ( more about its history ). It is an extensible and integrative portal which provides access to over 160 databases and software tools, developed by SIB Groups and supporting a range of life science and clinical research domains, from genomics, proteomics ...

  9. Compute various physical and chemical parameters for a given protein sequence. The computed parameters include the molecular weight, theoretical pI (isoelectric point), amino acid composition, atomic composition, extinction coefficient, estimated half-life, instability index, aliphatic index and grand average of hydropathicity (GRAVY).

  10. Translate. Genomics. Proteins & Proteomes. Software tool. Translation of a nucleotide (DNA/RNA) sequence to a protein sequence. Browse the resource website. Developed by the Swiss-Prot group and supported by the SIB Swiss Institute of Bioinformatics.

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