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  1. Jun 19, 2024 · Sickle-cell disease is characterized by a modification in the shape of the red blood cell from a smooth, donut-shape into a crescent or half moon shape. The misshapen cells lack plasticity and can block small blood vessels, impairing blood flow. This condition leads to shortened red blood cell survival, and subsequent anaemia, often called ...

  2. Jun 19, 2024 · Brazzaville – World Health Organization (WHO) in the African Region today released groundbreaking new guidance to help strengthen efforts to address the growing threat of sickle cell disease in the region. Significant for their integrated and holistic approach, the new technical documents offer detailed, actionable strategies and insights to support countries to improve quality of care, make ...

  3. The SICKLE technical package provides a holistic and integrated approach to managing sickle cell disease, ensuring access to necessary interventions, promoting education and advocacy, enhancing the quality of care, and empowering patients and communities.

  4. Sickle cell disease (SCD), or sickle cell anaemia, is a major genetic disease that affects most countries in the African Region. In sickle cell disease, the normal round shape of red blood cells become like crescent moons. Round red blood cells can move easily through the blood vessels but sickled shaped cells interconnect and can result in blood clots.

  5. Aug 23, 2022 · Sickle cell disease is an inherited blood disorder that shortens red blood cell survival, causing anaemia—often called sickle cell anaemia. Poor blood oxygen levels and blood vessel blockages in people with sickle cell disease can cause extreme pain in the back, chest, hands and feet as well as severe bacterial infections.

  6. Jul 17, 2018 · Sickle Cell Disease (SCD) belongs to a group of inherited red blood cell disorders. It happens when a child receives two sickle cell genes—one from each parent. The red blood cells become hard and sticky and look like a C-shaped farm tool called a “sickle”. SCD affects millions of people throughout the world. Approximately 300,000 ...

  7. Jun 21, 2024 · Opening Remarks by WHO Regional Director for Africa, Dr Matshidiso Moeti Excellencies, Ladies and gentlemen, Thank you for joining us today to commemorate World Sickle Cell Day. While this disease is a devastating life-long health issue that primarily affects people of African descent and the Middle East, the burden is rising globally. About 23 high-burden countries in West and Central Africa ...

  8. WHO SICKLE Package of Interventions for Sickle Cell Disease Management 1. Background Insight into Sickle Cell Disease Module 2 1.1 Rationale Sickle-cell disease (SCD) is the most common genetic disease, affecting 0.5–2% of newborns in Africa, but it is neglected despite its seriousness. Common

  9. Jun 19, 2019 · Sickle cell disease is a major genetic ailment that affects most countries in the African region of the World Health Organization (WHO). The condition distorts the shape of the red blood cells, changing them from round to sickle-shaped which means that they can hold less oxygen and are more likely to clump together to form clots.

  10. Jun 17, 2016 · Kampala, 17th June 2016 - Northern Uganda has the highest prevalence of Sickle cell trait and malaria in the country standing at 18.6% and (63%) respectively .This was revealed in a Sickle cell survey done in 2014 by the Ministry of Health (MoH) with support from Makerere College of Health Sciences and Cincinnati Children’s hospital. The study further revealed that East-Central regions come ...