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  1. Santa Cruz de la Sierra (Spanish: [ˈsanta ˈkɾus ðe la ˈsjera]; lit. "Holy Cross of the Mountain Range"), commonly known as Santa Cruz, is the largest city in Bolivia and the capital of the Santa Cruz department.

    • Climb the Cathedral of Santa Cruz. Located in the center of Santa Cruz at the Plaza 24 de Septiembre is the Cathedral of Santa Cruz. This beautiful cathedral is one of the best places to visit in the city.
    • Take a tour to Amboro National Park. Amboro National Park is a wildlife lover’s paradise and a visit is easily one of the best things to do in Santa Cruz!
    • See sloths on a nature and wildlife tour. Sloths in Bolivia are common even in urban areas but if you don’t have a trained eye it will be difficult to spot them on your own.
    • Learn the history of Santa Cruz on a walking tour. If you are a history buff or just like learning some history about the places you visit then you really can’t go wrong by going on a historical walking tour.
    • Jardín Botánico. Santa Cruz's lush botanical gardens, 12km east of the city center, make for a tranquil escape from the urban scene. Covering more than 200 hectares, the…
    • Basílica Menor de San Lorenzo. Although the original cathedral on Plaza 24 de Septiembre was founded in 1605, the present structure dates from 1845 and wasn’t consecrated until 1915…
    • Bell Tower. There are good city views of Santa Cruz from the bell tower of the Basilica Menor de San Lorenzo.
    • Lomas de Arena. This protected area, 12km south of Santa Cruz, is a strange and striking sandy desert that seems out of place in Santa Cruz's humid environs.
  2. Aug 30, 2021 · Things to Do in Santa Cruz, Bolivia: See Tripadvisor's 27,132 traveler reviews and photos of Santa Cruz tourist attractions. Find what to do today, this weekend, or in July. We have reviews of the best places to see in Santa Cruz. Visit top-rated & must-see attractions.

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  3. Located at the foothills of the Andes, Santa Cruz is not only the main hub for flights in and out of the country, but the gateway to some of Bolivia’s most adventurous outdoor activities. From wildlife watching and sand boarding to river rafting and hiking, there’s something to suit every travel-taste.

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  4. Mar 8, 2024 · Santa Cruz (or Santa Cruz de la Sierra) is the most populous city and heart of the second most populous metropolitan area in Bolivia, and is the capital of the department of Santa Cruz. It is considered the most economically prosperous city in the country.

  5. Feb 3, 2021 · Santa Cruz is a cosmopolitan city and a hub for exploring eastern Bolivia's natural and cultural attractions. Learn about its transport, accommodation, dining, and sightseeing options in this insider's guide.

  1. Book Hotels in Santa Cruz, Bolivia. Browse Reviews & Photos. Compare Great Options. Browse the Photos and Get Inspired. Start Planning Your Next Getaway.