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Jeffrey M. Friedman is a molecular geneticist and a Howard Hughes Medical Institute Investigator at Rockefeller University. He discovered the hormone leptin and its role in regulating body weight, and received many awards and honors for his research on obesity and aging.
Jeffrey Friedman (1959-2022) was an American political scientist and editor of Critical Review. He wrote books on rational choice, financial crisis and technocracy.
Dec 4, 2022 · A tribute to the late political theorist Jeffrey Friedman, who edited Critical Review and wrote on democracy, political knowledge, and libertarianism. Ilya Somin, a former student and colleague, recounts his influence and legacy.
- Ilya Somin
- George Mason University
- Professor of Law
Jeffrey Friedman is an American filmmaker who has won several awards with Rob Epstein for their documentaries on LGBTQ history and culture. Learn about his career, filmography, and collaborations with Scorsese, Hoffman, and Mac.
- Cholecystokinin
- Molecular Cloning of Leptin and Its Receptors
- Genetic Basis of Obesity in Humans
- Future Plans
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Although the physiological regulation of body weight and appetite has been strongly suggested by experimental evidence, the elucidation of the relevant molecular mechanisms has proven difficult. The possible role of a brain-gut peptide, cholecystokinin (CCK), in these processes was the initial subject of investigation in this laboratory. CCK has be...
Mutations in the mouse ob and db genes result in obesity and diabetes in a syndrome resembling morbid human obesity11, 12. Coleman, using the method of parabiosis, predicted that the ob gene encoded a novel hormone and that the db gene encoded its receptor11. Recent data from this laboratory are consistent with this hypothesis. The ob gene was iden...
Advances in genetics make it possible to identify human disease genes. The implementation of a genetic approach to the study of obesity will help establish whether the human ob or db genes account for genetic forms of obesity and also lead to the identification or validation of other candidate genes. Such studies require that large numbers of famil...
Future studies will also focus on the physiologic effects of leptin. These include studies of leptin's effects on lipid metabolism, glucose metabolism and insulin action. Available data suggest that neurons in the hypothalamus are a principle target of leptin actin. Studies to establish the neurotransmitter profile and projection of Ob-Rb positive ...
Jeffrey Friedman is a professor and investigator at Rockefeller University who studies the genetics and molecular mechanisms of obesity and diabetes. He discovered leptin, a hormone that regulates body weight, and cloned its receptor and gene.
"In this deeply learned, passionately argued book, Jeffrey Friedman offers a trenchant critique of technocracy that indicts both the epistocratic 'rule of experts' and the opinion-based policy produced by democratic collectives.
Jeffrey Friedman. Harvard University. No verified email - Homepage. ... J Friedman, S Friedman. Routledge, 2013. 21: 2013: Motivated skepticism or inevitable conviction?
